Herpes Zoster: Clinical Manifestation, Treatment, and Prevention

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Incidence, risk factors and prevention of herpes zoster: review article

Herpes zoster (Shingles; Zona) is an acute infectious skin disease that is caused by the reactivation of varicella zoster virus (VZV). After the initial infection (chickenpox) or vaccination, the virus remains inactive or latent in the dorsal root ganglia (DRG); when decreasing cell mediated immunity (CMI) occurs, the virus is reactivated from a latent phase to a lytic phase and frequently repl...

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Variations in herpes zoster manifestation

Herpes zoster (HZ) is a neurocutaneous disorder due to endogenous reactivation of the varicella-zoster virus (VZV). The typical clinical manifestation is an acute segmental eruption of herpetiform umbilicated vesicles associated with malaise, pain, dysaesthesia, allodynia and probably fever. This review focuses on other possible clinical manifestations of the disease to sensitize physicians not...

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Clinical efficacy and tolerability of valacyclovir versus acyclovir in treatment of herpes zoster

Background: Acyclovir, a specific and selective inhibitor of replication of herpesviridae family, has well documented efficacy for speedy rash healing and decreasing pain of herpes zoster. Limited oral bioavailability of acyclovir requires frequent dosing. Valacyclovir is rapidly and almost completely converted to acyclovir in vivo and gives three to fivefold increase in acyclovir bioavailabili...

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Treatment of herpes zoster.

OBJECTIVE To review the evidence regarding treatment of herpes zoster (HZ) in the short-term, focusing on the prevention of postherpetic neuralgia (PHN). QUALITY OF EVIDENCE The evidence relating to treatment of HZ is derived mainly from randomized controlled trials (level I evidence). MAIN MESSAGE Antiviral drugs might have some effect on the severity of acute pain and on the duration of s...

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Herpes Zoster: A Clinical Review

St. Mary’s Hospital, Division of Infectious Diseases, Waterbury, Connecticut, USA. Received for publication: August 13, 2011. Reprint request: Birinder S. Singh, M.D., St. Mary’s Hospital, Division of Infectious Diseases, Waterbury, Connecticut, USA. INTRODUCTION Varicella zoster virus (VZV) is a ubiquitous human virus that belongs to the subfamily alphaherpesvirinae.1 It contains the smallest ...

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ژورنال

عنوان ژورنال: Bioscientia Medicina : Journal of Biomedicine and Translational Research

سال: 2020

ISSN: 2598-0580

DOI: 10.32539/bsm.v4i3.129